2-(Trifluoromethoxy)benzene-1,4-dicarboxylic acid

2-(Trifluoromethoxy)benzene-1,4-dicarboxylic acid - Names and Identifiers

Name	2-(trifluoromethoxy)terephthalic acid
Synonyms	RARECHEM AL BO 0792 2-(Trifluoromethoxy)thiophenol 2-(TRIFLUOROMETHOXY)THIOPHENOL 2-(Trifluoromethoxy)terephthalic 2-(Trifluoromethoxy)benzenethiol 2-(Trifluoromethoxy)terephthalic acid 2-(TRIFLUOROMETHOXY)TEREPHTHALIC ACID 2-(trifluoromethoxy)terephthalic acid 2-(Trifluoromethoxy)benzene-1,4-dicarboxylic acid 2-(trifluoroMethoxy)-1,4-Benzenedicarboxylic acid 2-(trifluoromethoxy)benzene-1,4-dicarboxylic acid
CAS	175278-21-4
InChI	InChI=1/C9H5F3O5/c10-9(11,12)17-6-3-4(7(13)14)1-2-5(6)8(15)16/h1-3H,(H,13,14)(H,15,16)

2-(Trifluoromethoxy)benzene-1,4-dicarboxylic acid - Physico-chemical Properties

Molecular Formula	C9H5F3O5
Molar Mass	250.13
Density	1.614g/cm³
Melting Point	270-272°C
Boling Point	53-55°C 15mm
Flash Point	166.8°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	1.45E-05mmHg at 25°C
Appearance	Solid
Color	Pale Yellow to Light Yellow
Storage Condition	Sealed in dry,2-8°C
Sensitive	Air Sensitive/Stench
Refractive Index	1.4768

2-(Trifluoromethoxy)benzene-1,4-dicarboxylic acid - Risk and Safety

Risk Codes	R34 - Causes burns R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves.
UN IDs	3261
Hazard Note	Irritant/Stench/Air Sensitive/Keep Cold

2-(Trifluoromethoxy)benzene-1,4-dicarboxylic acid - Introduction

2-(trifluoromethoxy) terephalic acid is an organic compound with the chemical formula C9H7F3O4. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2-(trifluoromethoxy)terephthalic acid is a white crystalline solid.
-Solubility: Soluble in many organic solvents, such as ethanol, dimethylformamide, etc.
-Melting point: About 150-152 ℃.

Use:
- 2-(trifluoromethoxy)terephthalic acid is an important organic synthesis intermediate, which has a wide range of applications in the preparation of drugs, pesticides and coordination compounds.
-In the medical field, it can be used as an intermediate for antiarrhythmic drugs.
-In the field of pesticides, it can be used as a starting material for research and development of new pesticides.
-In the synthesis of coordination compounds, it can be used as a ligand to participate in the synthesis of metal complexes.

Method:
- 2-(trifluoromethoxy)terephthalic acid can be prepared by esterification of p-fluorobenzyl alcohol with P-Toluic acid. The reaction is usually carried out under acidic conditions, and an acid catalyst such as sulfuric acid may be used.

Safety Information:
- 2-(trifluoromethoxy) terephalic acid has high security, but the following matters still need to be paid attention:
-During operation, avoid prolonged inhalation of dust or contact with skin and eyes.
-It is recommended to operate in a well-ventilated environment and wear suitable protective equipment such as gloves and glasses.
-If you accidentally come into contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-Please store the compound in a sealed container, avoid contact with oxygen, oxidant or high temperature and other substances to prevent fire or explosion.

Last Update：2024-04-09 15:17:54